We are the Armenise–Harvard Laboratory of Genome Architecting at the University of Turin in Italy
We tackle a central challenge in biology: how to turn pluripotent stem cells into mature muscle cells at scale.
This question bridges two urgent goals:
In regenerative medicine, mature human cardiomyocytes are needed to safely remuscularize the heart.
In cellular agriculture, livestock mature myocytes can produce nutritious meat and seafood
Both fields face the same scale up barriers: by uncovering the molecular rules of this process, we aim to engineer cells that can both heal and nourish.
This question bridges two urgent goals:
In regenerative medicine, mature human cardiomyocytes are needed to safely remuscularize the heart.
In cellular agriculture, livestock mature myocytes can produce nutritious meat and seafood
Both fields face the same scale up barriers: by uncovering the molecular rules of this process, we aim to engineer cells that can both heal and nourish.
Our laboratory is based at the Molecular Biotechnology Center "Guido Tarone"
and the Department of Molecular Biotechnology and Health Sciences
and the Department of Molecular Biotechnology and Health Sciences
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We are supported by the Giovanni Armenise–Harvard Foundation and the European Research Council (StG #101076026), with additional funding by MUR, Additional Ventures, FEBS, and Compagnia di SanPaolo
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